Proper Manuscript Format

A reader writes to ask:

I have perused your formatting advice and have a question. You advise underline to indicate italics, what about bold? Make it "actual" or use asterisks, etc.? I need to indicate vectors in bold for a fact article but for Sci-fi geared magazine. Thanks

The use of boldface type is rare enough (at least in the fiction world) that, back in the olden days, one had to indicate it by hand by drawing a squiggly line underneath the words to be bolded. For whatever reason, our society has adopted italics as the preferred method of emphasis, which is why underling is a function readily available on most typewriters but undersquiggling is not.

Boldface is, however, more common in non-fiction. In cases where it may indeed be required, either by a publication's style guide or by conventions you've adopted for a specific article, I would just go ahead and use the actual bold function of your word processor. You are unlikely these days to submit a manuscript on paper, and using asterisks around the words to be bolded is likely just to result in mistakes in the final copy.